DGAT1 Participates in the Effect of HNF4A on Hepatic Secretion of Triglyceride-Rich Lipoproteins
نویسندگان
چکیده
منابع مشابه
DGAT1 participates in the effect of HNF4A on hepatic secretion of triglyceride-rich lipoproteins.
OBJECTIVE Hepatocyte nuclear factor-4alpha (HNF4A) is a transcription factor that influences plasma triglyceride metabolism via an as of yet unknown mechanism. In this study, we searched for the critical protein that mediates this effect using different human model systems. METHODS AND RESULTS Up- and downregulation of HNF4A in human hepatoma Huh7 and HepG2 cells was associated with marked ch...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2010
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.109.201426